Urology News Feeds
Intra-abdominal adhesions are a common complication following any surgical procedure involving the abdominopelvic cavity. The mechanism behind adhesion formation is still not well understood, however is thought to be caused from inflammatory signaling and mesothelial surface disruption.1 Adhesion occurrence following a laparotomy is estimated to be as high as 95%1 with the other two main causes of adhesion formation being chronic inflammation of the bowel and post radiation therapy.2,3,4 Bladder perforation due to intra-abdominal adhesions has never been reported but may be something to consider when other causes of peritonitis have been excluded.
Perioperative Hypoxia Secondary to Phenazopyridine-Induced Methemoglobinemia in an Adolescent Patient Without Renal Insufficiency or Overdose: An Unusual Case
Phenazopyridine is a common, well tolerated medication with minimal side effects. Severe side effects are rare and include methemoglobinemia in setting of overdose, elderly patients, renal insufficiency and chronic use.Here we report a case of methemoglobinemia induced perioperative hypoxia in an adolescent patient without renal insufficiency or overdose which has not been reported previously. This case underscores the importance of judicious use of this medication in all patients but notably in pediatric patients and those with chronic lung disease.
Baseline basal cell hyperplasia is not associated with baseline lower urinary tract symptoms, baseline clinical prostatitis or prostate cancer in repeat biopsies
To evaluate whether the presence of BCH in negative biopsies is associated with concurrent lower urinary tract symptoms(LUTS) and BPH, clinical prostatitis and future prostate cancer (PCa) in repeat prostate biopsy.
The Denys-Drash syndrome consists of a triad of ambiguous genitalia, Wilm's tumor and nephrotic syndrome. We present a diagnostically challenging case of an XY patient with female appearance and Müllerian structures with a WT1 mutation resulting in gonadal dysgenesis, end-stage renal disease, and precursor changes to Wilm's tumor in both kidneys. Genetic testing proved critical in this case, helping to solidify a diagnosis and guiding our decision to proceed with bilateral nephrectomy and bilateral gonadectomy.
OUTCOMES OF PARTIAL AND RADICAL NEPHRECTOMY IN OCTOGENARIANS – A MULTICENTER INTERNATIONAL STUDY (RESURGE)
To analyze the outcomes of partial nephrectomy (PN) and radical nephrectomy (RN) in octogenarian patients.
A Comparison of Hemostatic Patches versus Pericardium Allograft for the Treatment of Complex Peyronie's Disease with Penile Prosthesis and Plaque Incision
To compare outcomes between hemostatic patches (HP) versus pericardium allografts (PA) for complex Peyronie's disease with erectile dysfunction managed with inflatable penile prosthesis (IPP) and plaque incision and grafting (PIG).
Safety and Efficacy of Collagenase Clostridium Histolyticum in Peyronie's Disease Men with Ventral Curvatures
To evaluate the safety and efficacy of collagenase clostridium histolyticum (CCH) in men with ventral penile curvatures secondary to Peyronie's Disease (PD).
Whole-Exome Sequencing Identifies Novel Heterozygous Mutation in RAF1 in Family with Neonatal Testicular Torsion
To investigate a genetic cause of neonatal testicular torsion in two siblings and paternal cryptorchidism in a Caucasian family without history of consanguinity, we performed whole exome sequencing
Paratesticular masses are a relatively common finding in males. The majority are benign, as opposed to testis masses, which tend to be malignant. Fibrous pseudotumors are rare, but are the third most common paratesticular tumor after adenomatoid and lipoma. The exact cause is unclear but likely from a fibroinflammatory reaction. Because of the non-specific findings on physical exam and scrotal ultrasound, patients may undergo scrotal exploration and occasionally orchiectomy, in spite of the benign nature of this lesion.
To describe our surgical experience for the treatment and management of extramammary Paget's disease (EMPD).
Complete ultrasound-guided percutaneous nephrolithotomy in prone and supine positions: A Randomized controlled study
To evaluate the safety, efficacy, adverse events and feasibility of ultrasound guided percutaneous nephrolithotomy (US-PCNL) in the management of large renal stones in supine and prone positions and to point out the practical considerations related to these techniques in comparison with standard PCNL.
Three cases of testicular adrenal rest tumors in congenital adrenal hyperplasia - a diagnostic and therapeutic challenge
A 23-year old man presented with massive enlargement of his testes. He had a known history of salt-wasting congenital adrenal hyperplasia due to 21-hydroxylase deficiency (CAH) and was on glucocorticoid and mineralocorticoid replacement since initial diagnosis at birth with a current treatment regimen of prednisolone 7.5 mg and fludrocortisone 75 µg daily. However, compliance was poor as reflected by hormonal control parameters out of target range (Table 1). Ultrasound of the testes revealed the presence of massive bilateral tumors with mixed hypo- and hyperechogenic appearance.
To evaluate the feasibility of routine outpatient management after robotic-assisted radical prostatectomy (RARP). Prostate cancer is indeed the second most common cancer in men. Surgical technics have evolved from open surgery to robot-assisted surgery with a reduction of postoperative complications. Such technical improvements associated with modern anesthesia allow outpatient surgery in various types of procedures.
Prospective Implementation of a Point-of-Care PCR-Based Detection Method to Guide Antibiotic Use Prior to Prostate Biopsy Compared to Targeted Prophylaxis and Physician Choice
To perform pilot testing regarding implementation of a point-of-care qPCR-based test (EST200) targeting bacterial clonal groups representing the majority of sepsis-causing E. coli before prostate biopsy to determine antibiotic selection.
To assess subjective and objective outcomes in incontinent patients following ‘out-in’ TOT, at >10-year follow-up; to evaluate effect on QoL and other urinary symptoms, late adverse events and predictive factors for failure.
Lower Genitourinary Foreign Bodies: An Institutional Experience and Description of a Novel, Minimally-Invasive Extraction Technique for Anterior Urethral Objects
To describe our experience with management of lower genitourinary foreign bodies (FBs); to introduce our novel, but simple and minimally-invasive retrieval method compared to standard techniques for anterior urethral FBs; and to propose a derived, practical management algorithm.
To examine the utility of the Neurogenic Bladder Symptom Score (NBSS) in adults with cerebral palsy (CP).
Prevalence, Doppler Ultrasound Findings, and Clinical Implications of the Nutcracker Phenomenon in Pediatric Varicoceles
To examine the implications of varicoceles and nutcracker phenomenon (NcP) in a large cohort of adolescent patients. Varicoceles are common in adolescent males, generating concerns regarding etiology and management. At our institution, Doppler ultrasound (US) of the renal vessels is routinely obtained with the goal of assessing for an associated nutcracker phenomenon.
Efficacy and Safety of Serenoa repens Extract among Patients with Benign Prostatic Hyperplasia in China: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial
To evaluate the efficacy and safety of Serenoa repens among patients with benign prostatic hyperplasia (LUTS/BPH) in China.
Whenever a male physician examines a female patient's breast or genitalia, it has long been standard practice to always require that a chaperone be present. On the other hand, there has been no widely-accepted expectation, when a woman physician examines the genitalia of her patient, whether male or female, that a chaperone should likewise be present. However, the winds may now be changing. #METOO movement is encouraging women to speak out against various forms of inappropriate behavior which, in the past, they might have tolerated in silence.