Urology News Feeds
To demonstrate indications, review tools and techniques, as well as abnormal findings when performing a retrograde pyelogram.
To show how to perform a robot-assisted partial nephrectomy and bilateral pyelolithotomy in ectopic pelvic kidneys. This is a congenital abnormality of position and rotation1 frequently associated with urolithiasis.2 Renal cell carcinoma is a very rare event in pelvic kidneys.3,4 These two findings in the same patient could be a surgical challenge and whenever possible a “one stage” treatment is preferred.
Factors influencing the feasibility of segmental artery clamping during retroperitoneal laparoscopic partial nephrectomy
To investigate factors that may predict successful precise segmental artery clamping during retroperitoneal laparoscopic partial nephrectomy (LPN) for treatment of T1 kidney tumor.
Letter to the Editor on: Bladder Agenesis and Associated Pelvic Arterial Anomaly in 2 Female Pediatric Patients
In their recently published case report, Lowery et al presented two patients with bladder agenesis and concomitant pelvic arterial anomaly and suggested the two anatomical variants are causally related.1 Bladder agenesis is extremely rare with only 25 live births recorded in the literature.2 With so few patients to study, much of what is known is through case reports such as Lowery's.
Editorial Comment/Author Response to "Letter to the Editor on: Bladder Agenesis and Associated Pelvic Arterial Anomaly in 2 Female Pediatric Patients" (#URL-D-19-00427)
Since bladder agenesis is exceedingly rare, it is likely that we will never know the etiology of this malformation, or whether it could be the end result shared by more than one mechanism of maldevelopment. We agree with the authors of the “Letter to the Editor” that most published bladder agenesis cases do not comment on presence or absence of anomalous pelvic arterial anatomy. Thus, the authors are likely correct that the vascular malformation is not the root cause in most bladder agenesis cases.
Contemporary Management of Incident Prostate Cancer in Large Community Urology Practices in the United States
To characterize the contemporary management of prostate cancer patients in large community practices. The optimal management of incident prostate cancer has changed in the last decades to include active surveillance for a large number of men. At the same time, many community practices have merged into larger groups. The adoption of evidence-based guidelines is of increasing importance, but poorly understood in this newer practice setting.
COMPARISON OF PATIENT'S SATISFACTION AND LONG-TERM RESULTS OF TWO PENILE PLICATION TECHNIQUES: LESSONS LEARNED FROM 387 PATIENTS WITH PENILE CURVATURE
To compare the patient's satisfaction and long-term results of two penile plication procedures in patients with penile curvature.
Increasing Utilization of Multi-Parametric Magnetic Resonance Imaging in Prostate Cancer Active Surveillance
To characterize the use of multiparametric magnetic resonance imaging (mpMRI) in male Medicare beneficiaries electing active surveillance for prostate cancer. Multi-parametric resonance imaging (mpMRI) has emerged as a tool that may improve risk-stratification and decrease repeated biopsies in men electing active surveillance. However, the extent to which mpMRI has been implemented in active surveillance has not been established.
To demonstrate technical considerations of a true single port robotic assisted ureteroneocytostomy using the da Vinci SP platform (Intuitive Surgical, Sunnyvale, CA).
A Case of Metastatic Prostate Cancer to the Urethra that Resolved after Androgen Deprivation Therapy
An 83 year-old male with Gleason score 4+3 prostatic adenocarcinoma status post brachytherapy developed obstructive voiding symptoms nine years after brachytherapy. PSA was 0.67. Cystoscopy noted multiple papillary urethral tumors concerning for primary urethral carcinoma. Immunophenotype of biopsies supported diagnosis of Gleason score 4+4 prostatic adenocarcinoma. Androgen deprivation therapy was started. Cystoscopy performed four years later, for microhematuria workup, noted complete resolution of the urethral tumors.
Urethral obstruction due to retained bullets migrating into the genitourinary system has rarely been reported. The literature describes two main methods of retained bullet removal from the genitourinary system: (1) spontaneous expulsion during voiding and (2) manual extraction due to urethral obstruction causing acute urinary retention. We present a case in which a 21-year-old man presented with acute urinary retention three years after suffering a gunshot wound to the abdomen. A retained bullet eroded through the bladder wall, migrated through the bladder and urethra, and eventually became lodged in the external urethral meatus, causing obstruction and urinary retention.
To evaluate the impact of cisplatin-based neoadjuvant chemotherapy (NAC) in patients who underwent nephroureterectomy for high grade (HG) upper tract urothelial carcinoma (UTUC).
Is Extraprostatic Extension of Cancer Predictable? A Review of Predictive Tools and an External Validation based on a Large and a Single Center Cohort of Prostate Cancer Patients
Our aim was to review and externally validate all the available predictive tools (PTs) predicting EPE using the area under the curve (AUC), calibration plots and scaled brier score.A literature search was performed showing 19 models predicting EPE. External validation (EV) was carried out on 6360 prostate cancer (PCa) patients submitted to RP. Most of the PTs showed poor discrimination and unsatisfactory calibration.The majority of the available PTs are not reliable for the prediction of EPE in populations other than the development one; thus, they may not be completely appropriate for patients’ counselling or for surgical strategy preplanning.
Location of recurrence by Gallium-68 PSMA-11 PET scan in prostate cancer patients eligible for salvage radiotherapy
To identify locations of recurrence after radical prostatectomy (RP) with PSA <2 by Gallium-68 Prostate Specific Membrane Antigen (PSMA)-11 PET imaging, and to determine whether standard nodal radiation fields would cover the location of prostate cancer recurrence.
“The Utility of Prostate Specific Antigen Density, Prostate Health Index and Prostate Health Index Density in Predicting Positive Prostate Biopsy Outcome is Dependent on the Prostate Biopsy Methods”
To evaluate prognostic markers, prostate-specific antigen (PSA), prostate health index (PHI) and prostate volume indexed measures (PSAD and PHID) for predicting positive prostate cancer biopsies in magnetic resonance (MR) transrectal ultrasound fused versus non-fused transrectal ultrasonography biopsy.
Right Testicular Infarction Secondary to Spontaneous Testicular Vein Thrombosis in a Child: Case Report and Literature Review
Pediatric testicular vein thrombosis is a rare entity with only six reported cases. Diagnosis depended on preoperative clinical suspicion, radiological and intraoperative findings. The literature is very limited in the pediatric population with different etiologies and different managements. We present a case of a 14-year-old boy who suffered from spontaneous right testicular vein thrombosis and was treated with right orchiectomy and oral anticoagulation. We also reviewed and summarized the previously described cases of pediatric testicular vein thrombosis.
Botulinum toxin type A injection after failure of augmentation enterocystoplasty performed for neurogenic detrusor overactivity: preliminary results of a salvage strategy. The ENTEROTOX study
To evaluate the clinical efficacy, urodynamic effect and safety of Botulinum Toxin A (BTXA) injections after failure of augmentation enterocystoplasty (AE) performed for NDO.
Whole Exome Sequencing Identifies a Rare Nonsense Mutation in FAM47C as a Possible Cause of Severe Oligospermia in Brothers with Varicocele
Varicocele is a common cause of impaired semen parameters in men with infertility. Here, we investigated genetic variants as possible causes of varicocele with impaired semen parameters using whole-exome sequencing (WES) in a family with 2 brothers with severe oligospermia, 1 unaffected brother, father, and the mother. Results showed a premature stop codon alteration on Chromosome X (37028866 CT) in the gene FAM47C. The affected brothers were found to be hemizygous for the variant, while the mother was a heterozygous carrier.
Avoiding the Need for Bowel Anastomosis during Pelvic Exenteration—Urinary Sigmoid or Descending Colon Conduit—Short and Long Term Complications
To educate surgeons of distal colon urinary diversion as an alternative to ileal conduit. To assess peri-operative outcomes of distal colon conduit in pelvic exenteration including conduit-related, gastrointestinal, infectious, metabolic, and wound complications within 30 days, 31-89 days, and greater than 90 days from the time of surgery.
A Novel Proteomics Approach to Identify Serum and Urinary Biomarkers and Pathways that Associate with Lower Urinary Tract Symptoms in Men and Women: Pilot Results of the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) Study
To assess the feasibility of a novel proteomics approach to identify biomarkers associated with LUTS within serum and urine, because many clinical factors contribute to lower urinary tract symptoms (LUTS) in men and women. These factors confound clinicians’ abilities to reliably evaluate and treat LUTS. Previous studies identified candidate LUTS biomarkers, but none are clinically utilized.