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Child development is often divided into normal development and developmental psychopathology. Recently, this latter division has burgeoned because of our increasing awareness of the harsh realities of adverse early events (AEEs) on child development. However, as a field of study child development suffers from at least 2 maladies: (1) developmentalists tend to be shortsighted, seeing child development as an independent field; (2) studies of developmental psychopathology focus almost entirely on external AEEs—that is, child abuse, trauma, or parenting failures.
Intravesical Electromotive Botulinum Toxin Type “A” Administration for Management of Urinary Incontinence Secondary to Neuropathic Detrusor Overactivity in Children: Long-Term Follow-up
To investigate the long-term efficacy and success rate of intravesical electromotive botulinum toxin type A (BoNTA) “Dysport®” administration in myelomeningocele (MMC) patients who had urinary incontinence due to neuropathic detrusor overactivity (NDO).
Anterior urethral syringocele is an uncommon congenital deformity characterised by cystic dilatation of bulbo-urethral gland ducts and is usually asymptomatic. We present a case on 4-day-old male neonate who presented with bilateral antenatal hydroureteronephrosis and renal impairment and found to have urethral syringocele and posterior urethral valves (PUV).
Renal gunshot wounds resulting in a grade IV injury (AAST) should be explored only if they involve the hilum or if there are signs of suspected renal pelvis or ureteral laceration, active haemorrhage, peritonitis or hemodynamically unstable patients.1 However, due to the paucity of cases reported in the literature, it is not clear what the best management of patients with a retained bullet is, which have been traditionally treated with surgical retrieval in other organs. We present the radiological findings and a clinical case summary of a patient with Grade IV kidney injury and retained bullet managed conservatively.
Anatomical Control of Adenoma (Ancona) Technique: an Accurate Surgical Approach to Thulium Laser Enucleation of the Prostate
To present our two-lobe technique of thulium laser transurethral enucleation of prostate. Transurethral resection of prostate and open prostatectomy (OP), have been traditionally considered the gold standard of benign prostatic enlargement (BPE) surgical treatment. Laser have been recently made available for BPE surgery, in order to minimize morbidity of traditional surgery1. In 2009 Bach introduced the use of thulium laser2, describing the 3-lobes technique, which overlaps OP but with a greater control of hemostasis3.
Clinical Utility and Biologic implications of Phosphatase and Tensin Homolog (PTEN) and ETS-related Gene (ERG) in Prostate Cancer
Phosphatase and Tensin Homolog (PTEN) and ETS-related Gene (ERG) mutations are commonly found in prostate cancer. Although mouse studies have demonstrated PTEN and ERG cooperatively interact during tumorigenesis, human studies examining these genes have been inconclusive. A systematic Pubmed search including original articles assessing the pathogenesis of PTEN and ERG in prostate cancer was performed. Studies examining ERG's prognostic significance have conflicting results. Studies examining PTEN and ERG simultaneously found these genes are likely to occur together but cooperative tumorigenesis functions have not been conclusively established.
Comparison of Adjuvant Radiation Therapy before or after Artificial Urinary Sphincter Placement: a Multi-Institutional, Retrospective Analysis
To determine if the timing of radiation therapy on artificial urinary sphincter (AUS) impacts complication rates, revision rates, and number of pads per day after placement.
Prostate Magnetic Resonance Imaging Provides Limited Incremental Value Over the Memorial Sloan Kettering Cancer Center Pre-Radical Prostatectomy Nomogram
To examine the incremental value of prostate MRI when used in combination with the currently available preoperative risk stratification tool the Memorial Sloan Kettering Cancer Center Pre-Radical Prostatectomy Nomogram (MSKCC).
To evaluate the presence and content of policies on posthumous sperm retrieval at 75 major academic medical centers in the U.S.
We thank Reynaldo Gomez for the editorial and positive comments toward our work. We have had a unique experience with early endoscopic realignment (EER) at our institution and appreciate the opportunity to share our results. We agree that the management of a pelvic fracture urethral injury (PFUI) may be selective with the option for EER if open reduction and internal fixation (ORIF) is considered mandatory and the option for immediate suprapubic tube (SPT) placement with delayed urethroplasty for the remaining patients.
Early management of pelvic fracture urethral injuries (PFUIs) continues to be a controversy between basically 2 treatment strategies. Strategy 1 (S1) is early endoscopic realignment (EER) passing a catheter across the injury that is left for 3-6 weeks allowing the tear to heal. The other strategy (S2) is immediate placement of a suprapubic cystostomy (SPT) leaving the urethra untouched, for a subsequent delayed perineal urethroplasty. Despite many publications, this is an unresolved dilemma because of the lack of prospective comparative studies and because of selection bias and variable definitions of success.
Inhibition of Jun N-Terminal Kinase (JNK) Improves Erectile Function by Alleviation of Cavernosal Apoptosis in a Rat Model of Cavernous Nerve Injury
To determine whether JNK inhibition could alleviate erectile dysfunction (ED) through suppressing cavernosal apoptosis in a rat model of carvernosal nerve crush injury (CNCI), thereby providing potential therapeutic strategy for alleviating post-radical prostatectomy (RP) ED.
A Novel Modification of Transurethral Enucleation and Resection of the Prostate in Patients with Prostate Glands Larger Than 80 Ml: Surgical Procedures and Clinical Outcomes
To evaluate efficacy and safety of the modified transurethral enucleation and resection of the prostate (M-TUERP) versus conventional bipolar transurethral resection of the prostate (B-TURP) for the treatment of prostates larger than 80 ml.
A man with left scrotal swelling felt to represent inguinal hernia underwent CT scan for reported bleeding after prostate biopsy. CT scan revealed a 15 cm extratesticular left scrotal mass containing both fat and soft tissue components, raising concern for dedifferentiated liposarcoma. At surgery and pathology, the mass was separate from the left testis, epididymis, and spermatic cord. Histopathologic findings were consistent with paratesticular dedifferentiated liposarcoma.
To identify the rate at which testicular torsion occurs in a lateral direction and identify any predictors of direction of testicular rotation and orchiectomy
Urethral adenocarcinoma of males is a rare disease with limited prospective data to define optimal treatment. Surgical excision remains the primary treatment for early stage disease. Multimodality therapy with a combination of chemotherapy, radiation, and/or surgery has been explored in patients with locally advanced disease. We present the case of a 45-year-old-man with a locally recurrent urethral adenocarcinoma after initial surgical resection managed successfully with combined weekly cisplatinum and radiation therapy.
We describe the imaging findings of a 19 year female who presented with recurrent urinary tract infections and pain abdomen which was diagnosed to be due to a left sided focal segmental megaureter with a calculus. The highlights of the case are functioning moiety with no other associated anomalies like VUR, Duplex system etc.
To create a simple neobladder and determine whether the double limb U-Pouch (DLUP) has the same capacity and compliance as a Studer or Camey I neobladder. To develop an orthotopic diversion that can be applied to robotic surgery with laboratory data supporting the concept.
ObjectiveTo evaluate the effect of conservative management of high-grade renal trauma on length of hospitalization, we aim to describe characteristics of patients with high-grade renal trauma that are associated with an increased length of stay (LOS) and the effect of conservative versus surgical management on hospital LOS.MethodsA retrospective review of all patients who suffered unilateral high-grade renal trauma (grade 3 or higher) from 9/1977 to 8/2012 at San Francisco General Hospital in San Francisco, CA was performed.
To develop recombinant lactic acid bacteria (LAB) strains that express oxalate-degrading enzymes through biotechnology-based approach for the treatment of hyperoxaluria by oral administration.