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Updated: 28 min 57 sec ago

Non-neuropathic Neuropathic Bladder: Is it Really Non-neuropathic?

Fri, 09/21/2018 - 00:00
Hinman Syndrome is a rare disease with urodynamic findings and clinical course that resemble neuropathic bladder and no neuropathic etiology. Diffusion Tensor Imaging (DTI) is a special magnetic resonance imaging (MRI) technique that has recently been used for peripheral nerves but shown to be applicable for evaluation of lumbosacral plexus. Our aim was to evaluate the lumbosacral plexus using DTI, which was not previously performed in Hinman Syndrome.
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Radical prostatectomy after vascular-targeted photodynamic therapy (VTP) with TOOKAD® : feasibility, early and intermediate results

Fri, 09/21/2018 - 00:00
and objectives: vascular-targeted photodynamic therapy with TOOKAD® (VTP) is a new therapeutic option for localized prostate cancer (PCa) management. The objectives are to assess the feasibility of radical prostatectomy (RP) after VTP and describe functional and oncological outcomes.
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Editorial Comment

Thu, 09/20/2018 - 00:00
It is exciting to see studies such as this one in which elegant technology was applied to improve medical decision making by using presumably more accurate means of prediction. In this case the example is machine learning to predict stone-free status after single session shock wave lithotripsy to treat ureteral stones. If the idea of seeing what machine learning can do for decision making does not excite you, just watch AlphaGo (DeepMind, London, United Kingdom) on Netflix®!
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Editorial Comment

Thu, 09/20/2018 - 00:00
The authors attempted to develop and validate a decision support model to predict treatment success after a single session of lithotripsy in patients with ureteral stones. They included 15 factors in decision making. While the stone characteristics included in the model, such as stone bulk, density and depth from the skin, have been significant in impacting fragmentation following lithotripsy, renal function, too, is a logical inclusion. However, the impact of patient characteristics like age, gender or body mass index on fragmentation following lithotripsy have been variable.
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Reply by Authors

Thu, 09/20/2018 - 00:00
It is unfortunate that Gold and Ende have misinterpreted the findings of our study in an attempt to support the integral theory. We believe the integral theory has no scientific validity and consider it a fallacy.
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Re: Correlations between Sonographic and Urodynamic Findings after Mid Urethral Sling Surgery

Thu, 09/20/2018 - 00:00
We congratulate the authors for accurately obtaining and presenting these data in clear, easy to understand images. Unfortunately their conclusion, ie the data support the notion that the mid urethral sling mechanism of action is dynamic urethral compression, is incorrect.
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Editorial Comment

Wed, 09/19/2018 - 00:00
This rapid review with practice recommendations on the treatment and prevention of recurrent lower urinary tract infections in women is timely as the number of women affected by this condition, especially the older group, is rapidly growing in all of our practices. The authors should be congratulated for their large and detailed search of the best available literature on this topic and for offering a succinct algorithm of the favored alternatives for rUTI prevention and treatment. Notably, a quick glance at reference 3 pointing out the lack of consensus in the definition of rUTIs, and at the quality rating (AMSTAR 2) column in table 3 documenting the “low or critically low” level of evidence in the presented data in 20 of 23 reviews, should be more than sufficient to convince the reader and the international scientific community of the vast gaps in knowledge of rUTIs.
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Editorial Comment

Wed, 09/19/2018 - 00:00
Recurrent lower urinary tract infections in women are a frustrating problem for patient and provider. Patients suffer with these infectious episodes, often at inconvenient times, and have very bothersome symptoms. Repeat courses of antibiotics put them at risk for yeast vaginitis and gastrointestinal disturbances including C. difficile colitis. These women also suffer from constant worry about when their next infection is going to strike.
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Editorial Comment

Wed, 09/19/2018 - 00:00
Urinary stone disease is a growing and important public health problem in the United States. Tundo et al report the results of a cross-sectional analysis of data from the 2007 to 2012 NHANES, the gold standard for nationally representative health estimates. Focusing on younger adults, the authors compared the prevalence of self-reported stone disease by gender, finding an equal prevalence of stones (approximately 1/16) among men and women. These findings persisted after controlling for important potential confounders.
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Active surveillance for localized prostate cancer. Nationwide, observational study

Tue, 09/18/2018 - 00:00
The objective of this study was to investigate nationwide survival outcomes in men with localized prostate cancer managed on active surveillance.
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6-month Results of Selective Bladder Denervation in Women with Refractory Overactive Bladder

Tue, 09/18/2018 - 00:00
To report 6-month efficacy and safety outcomes with selective bladder denervation in women with refractory OAB.
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Defining Intermediate-Risk Prostate Cancer Suitable for Active Surveillance

Tue, 09/18/2018 - 00:00
Active surveillance (AS) for intermediate-risk prostate cancer (PCa) is controversial. Many AS programs are limited to grade group (GG) 1 (Gleason 6) and PSA<10 ng/ml. However, recent guidelines state that AS can be considered for limited GG2 (Gleason 3+4), despite limited data on outcomes. Our objective was to compare prostatectomy outcomes between subgroups of intermediate-risk versus low-risk PCa.
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Characterization of a Standardized Postoperative Radiographic and Functional Voiding Trial after One-Stage Bulbar Ventral Onlay Buccal Mucosal Graft Urethroplasty and the Impact on Stricture Recurrence-Free Survival

Tue, 09/18/2018 - 00:00
To characterize a standardized postoperative radiographic and functional voiding trial and determine its impact on outcomes after substitution urethroplasty.
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Hypospadias as a Chronic Illness

Mon, 09/17/2018 - 00:00
Once a surgical procedure is completed, the duration of followup is determined by the risk of complications. After a routine circumcision one has a single followup and, if all is well, is discharged home. In contrast, penile reconstruction for hypospadias repair has a greater risk of complication development. The general consensus is that the complication rate for distal hypospadias is close to 10%. However, more recent studies have shown that with extended followup proximal repairs have a much more grim outcome.
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Re: In Vivo Replacement of Damaged Bladder Urothelium by Wolffian Duct Epithelial Cells

Mon, 09/17/2018 - 00:00
D. B. Joseph, A. S. Chandrashekar, L. L. Abler, L. F. Chu, J. A. Thomson, C. Mendelsohn and C. M. Vezina
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Re: Patterns of Medical Management of Overactive Bladder (OAB) and Benign Prostatic Hyperplasia (BPH) in the United States

Mon, 09/17/2018 - 00:00
J. T. Anger, H. B. Goldman, X. Luo, M. O. Carlsson, D. Chapman, K. H. Zou, D. Russell, F. Ntanios, C. B. Esinduy and J. Q. Clemens
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Re: A Systematic Review on Vaginal Laser Therapy for Treating Stress Urinary Incontinence: Do we Have Enough Evidence?

Mon, 09/17/2018 - 00:00
V. Pergialiotis, A. Prodromidou, D. N. Perrea and S. K. Doumouchtsis
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Re: Intraductal/Ductal Histology and Lymphovascular Invasion Are Associated with Germline DNA-Repair Gene Mutations in Prostate Cancer

Mon, 09/17/2018 - 00:00
P. Isaacsson Velho, J. L. Silberstein, M. C. Markowski, J. Luo, T. L. Lotan, W. B. Isaacs and E. S. Antonarakis
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