Journal of Urology ( White Journal) In Press
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To assess focal therapy (FT) eligibility among men receiving multiparametric magnetic resonance imaging (mpMRI) and targeted biopsy, with correlation to whole mount histology after radical prostatectomy (RP).
Bladder Reconstruction Rates Differ Among Centers Participating in National Spina Bifida Patient Registry
We performed an exploratory analysis of data from the National Spina Bifida Patient Registry (NSBPR) to assess variation in the frequency of bladder reconstruction surgeries among NSBPR centers.
Re: Who Gets Testosterone? Patient Characteristics Associated with Testosterone Prescribing in the Veteran Affairs System: A Cross-Sectional Study
G. K. Jasuja, S. Bhasin, J. I. Reisman, J. T. Hanlon, D. R. Miller, A. P. Morreale, L. M. Pogach, F. E. Cunningham, A. Park, D. R. Berlowitz and A. J. Rose
D. L. Dräger, C. Protzel and O. W. Hakenberg
Re: Evaluation and Establishment of a Ward-Based Geriatric Liaison Service for Older Urological Surgical Patients: Proactive Care of Older People Undergoing Surgery (POPS)-Urology
P. Braude, A. Goodman, T. Elias, G. Babic-Illman, B. Challacombe, D. Harari and J. K. Dhesi
Re: Identifying Prevalence and Risk Factors for Mild Cognitive Impairment in Adults Presenting for Urological Evaluation
G. Roberge, S. K. Stortz, W. C. Frankel, K. L. Greene and D. Y. Deng
Re: The Near-Future Impact of Retirement on the Urologic Workforce: Results from the American Urological Association Census
T. W. Gaither, M. A. Awad, R. Fang, J. Q. Clemens, W. Meeks, S. Gulig, B. A. Erickson, P. H. McKenna, C. M. Gonzalez, E. C. Osterberg and B. N. Breyer
Long Term PSA Stability and Predictive Factors of Failure after Permanent Seed Prostate Brachytherapy
Defining biochemical failure as nadir+2 may overestimate cure after radiotherapy. We assess long term PSA stability after low dose rate prostate brachytherapy and predictors of biochemical failure when the PSA is slowly rising below the nadir + 2 ng/ml threshold.
Infection stones comprise approximately 15% of all urinary tract stones and are induced by infection with urease-positive pathogens. The bacteria within the stone matrix present significant treatment impediments compared to metabolic kidney stones. While much is known about how urinary composition regulates metabolic stone formation, there is a general lack of knowledge around which urinary factors regulate the rate of infection stone formation. Unfortunately, more in-depth research into infection stones is limited by the lack of suitable models for the real-time study of bacterial biofilm formation and stone formation under varying conditions.
Delayed Reconstruction of Bulbar Urethral Strictures is Associated with Multiple Interventions, Longer Strictures, and More Complex Repairs
Prior to urethral reconstruction, many stricture patients undergo a variable period during which endoscopic treatments are employed for recurrent obstructive symptoms. We evaluate the association between urethroplasty delay, endoscopic treatments, and subsequent reconstructive outcomes.
Efficacy and Safety of Enzalutamide vs Bicalutamide in Younger and Older Patients with Metastatic Castration-resistant Prostate Cancer in the TERRAIN Trial
Enzalutamide significantly prolonged median progression-free survival vs bicalutamide in chemotherapy-naïve metastatic castration-resistant prostate cancer in TERRAIN. A post hoc analysis investigated the influence of age on efficacy and safety of enzalutamide vs bicalutamide in this population.
Comprehensive Evaluation of Prostate-Specific Membrane Antigen Expression in the Vasculature of Renal Tumors: Implications for Imaging Studies and Prognostic Role
Prostate-specific membrane antigen (PSMA) is expressed by endothelium of many tumors. The aim of the study was to find a rationale for PSMA-based imaging and to investigate the prognostic role of vascular PSMA expression in patients with renal cell carcinoma (RCC).
The biological basis for our understanding of kidney cancer has increased dramatically in the last decade as advances in genomic studies and refinements in tumor sub-classification have coupled with robust clinical databases to yield a wealth of information relevant to patient outcomes. Excellent studies developed from such resources have offered the practicing urologist valuable tools to provide patients with detailed advice and to engage in a thoughtful process for shared decision making. Improving the accuracy of pretreatment risk stratification models has become a major endeavor, including biopsy in selected patients.
Renal abnormalities thought to be malignant should be managed as such. We all agree on that. The differences in opinion arise regarding how accurate that determination of malignancy needs to be and how to make that determination before deciding on a course of action. Historically imaging has been used, initially with intravenous urography and later with ultrasonography, computerized tomography and/or magnetic resonance imaging. In general, abnormalities that appeared solid without features notable for specific benign lesions such as angiomyolipomas were presumed malignant.
Opioid prescription is as deeply entrenched in the rituals of surgery as the act of donning gown and gloves. The ability to perform surgical interventions has always depended on the availability of analgesia and opioids have long represented an indispensable component of care. Currently, a spotlight illuminates a national epidemic of opioid misuse, with soaring rates of dependence, chronic use and overdose related to prescribed and illicit formulations. Indeed, it is estimated that in 2015, 11.5 million Americans (4.5%) misused opioids and that 1.9 million (0.8%) had a use disorder.
Surgical and patient-reported outcomes of artificial urinary sphincter implantation: A multicenter, prospective, observational study
To assess outcomes, including changes in continence status and quality of life (QOL), after artificial urinary sphincter (AUS) implantation, a multicenter, prospective, observational study was conducted.
Partial gland ablation versus radical prostatectomy Comparative Analysis of Partial Gland Ablation and Radical Prostatectomy to Treat Low- and Intermediate-risk Prostate Cancer: Oncologic and Functional Outcomes
To analyze oncologic and functional outcomes of partial gland ablation (PGA) compared with robot-assisted radical prostatectomy (RARP) for patients with low-and intermediate-risk prostate cancer.
Re: Association between Joint Hypermobility and Pelvic Organ Prolapse in Women: A Systematic Review and Meta-Analysis
N. Veit-Rubin, R. Cartwright, A. U. Singh, G. A. Digesu, R. Fernando and V. Khullar
K. J. Thomas-White, S. Kliethermes, L. Rickey, E. S. Lukacz, H. E. Richter, P. Moalli, P. Zimmern, P. Norton, J. W. Kusek, A. J. Wolfe and L. Brubaker; National Institute of Diabetes and Digestive and Kidney Diseases Urinary Incontinence Treatment Network