Urology News Feeds

Emerging complications following alternative reservoir placement during inflatable penile prosthesis placement: a 5-year multi-institutional experience.

Alternative, or ectopic, reservoir placement (ARP) has recently gained popularity among prosthetic surgeons in order to avoid injury to pelvic structures during inflatable penile prosthesis (IPP) implantation. However, the true incidence of complications associated with these new techniques remain understudied. We carried out a 5-year multi-center retrospective study with the aim to evaluate complications related to alternative reservoir placement.
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A serrated hyperplastic colonic polyp of the urinary bladder

Urology (Gold Journal) In Press - Mon, 10/22/2018 - 00:00
Intestinal metaplasia of the urinary bladder can occur within the surface urothelium due to chronic irritation in repaired exstrophic urinary bladder. Colonic villous adenomas and tubulovillous adenomas with high grade dysplasia and associated adenocarcinoma have been reported in adult patients with a history of augmented exstrophic bladder. To our knowledge, we report the first example of a non-adenomatous serrated hyperplastic colonic polyp in an elderly patient with a history of exstrophic bladder.
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Reduced Recurrence of Low-Grade Papillary Bladder Tumors Associated with Asymptomatic Bacteriuria

Urology (Gold Journal) In Press - Mon, 10/22/2018 - 00:00
To determine tumor recurrence rate of low-grade, papillary, non-muscle-invasive (TaLG) bladder tumors in patients who have asymptomatic bacteriuria (ABU). Microbes in the urine trigger immune responses like intravesical BCG, suggesting that common bacteria may also exert an antitumor effect.
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An Infertile Couple's Long and Expensive Path to Varicocele Repairs

Urology (Gold Journal) In Press - Mon, 10/22/2018 - 00:00
To characterize the pathways to care that infertile couples requiring varicocele repair (VR) pursue prior to presenting to a male fertility clinic.
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Extreme Price Variation for Generic Benign Prostatic Hyperplasia Medications

Urology (Gold Journal) In Press - Mon, 10/22/2018 - 00:00
To characterize geographic variability of generic benign prostatic hyperplasia (BPH) medications in order to improve drug price transparency and improve patient access to affordable medication sources. This is of interest because BPH is one of the most common chronic diseases in men and contributes to individual healthcare cost. Medical therapy is the main treatment modality for BPH, burdening patients with lifelong medication expenses which may impact adherence and subsequent outcomes. With an aging population, this is compounded by many older individuals requiring multiple daily medications.
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An antenatally detected pure malignant rhabdoid tumour of the bladder

Urology (Gold Journal) In Press - Mon, 10/22/2018 - 00:00
Pediatric malignant rhabdoid tumours are a rare entity with poor prognosis. The extra-renal variants of this disease are sparsely presented within the literature. Our case represents, to our knowledge, the first antenatally detected bladder-variant. At nineteen-months of age, this patient has benefited from early detection and intervention and remains disease free following partial cystectomy and chemotherapy.
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Proteinaceous renal stones in a kidney transplant candidate presenting as bilateral filling defects suspicious for upper urinary tract transitional cell carcinoma

Urology (Gold Journal) In Press - Mon, 10/22/2018 - 00:00
Our patient is a 60-year-old female with a past medical history significant for diabetes mellitus type 2, smoking, anal cancer status-post transrectal excision with no evidence of recurrence or metastasis, rheumatoid arthritis, systemic lupus erythematosus and end-stage renal disease (ESRD) on hemodialysis (HD). She had progressive chronic kidney disease for approximately 25 years, ultimately starting HD 3 years prior to this evaluation. She presented to the urology department for evaluation prior to kidney transplantation.
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Risk of Ovarian Malignancy in Patients Undergoing Radical Cystectomy for Bladder Cancer

Urology (Gold Journal) In Press - Mon, 10/22/2018 - 00:00
To determine whether there is an increased risk of ovarian cancer in women undergoing radical cystectomy for bladder cancer using a large population-based data source. Current American Urologic Association guidelines suggest removal of ovaries during RC in women with bladder cancer, presumably to mitigate the risk ovarian cancer. However, recent data have demonstrated an increased risk of all-cause mortality, cardiovascular disease, osteoporosis, cognitive impairment and diminished sexual function in some populations of women after oophorectomy.
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Perioperative Intravesical Chemotherapy for Patients with Non-Muscle Invasive Bladder Cancer: Understanding the Extent of and Sources of Variation in Guideline-Recommended Use

Urology (Gold Journal) In Press - Mon, 10/22/2018 - 00:00
To examine intravesical chemotherapy (IVC) use according to non-muscle invasive bladder cancer (NMIBC) patient disease risk, and the contributions of multi-level factors to variation in proficient use among patients with low-intermediate disease.
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Combined ischemic postconditioning and ozone postconditioning provides synergistic protection against renal ischemia and reperfusion injury through inhibiting pyroptosis

Urology (Gold Journal) In Press - Mon, 10/22/2018 - 00:00
To investigate whether ischemic postconditioning(IPO) and ozone postconditioning(OP) could synergistically attenuate renal ischemia and reperfusion (I/R) injury and its possible mechanism.
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Effects of a Novel Piezo Actuator-Driven Pulsed Water Jet System on Residual Kidney after Partial Nephrectomy in a Rat Model

Urology (Gold Journal) In Press - Mon, 10/22/2018 - 00:00
To evaluate renal damage after off-clamp partial nephrectomy using a novel surgical device, piezo actuator-driven pulsed water jet system.
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Long-term discontinuations of botulinum toxin A intradetrusor injections for neurogenic detrusor overactivity: a multicenter study

Data on long-term outcomes of intradetrusor injections of botulinum toxin A (BTX-A) for neurogenic detrusor overactivity (NDO) are lacking. The aim of the present manuscript was to assess the outcomes of intradetrusor injections of BTX-A for NDO after more than 10 years of follow-up.
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Perioperative Oral Nutrition Supplementation Reduces Prevalence of Sarcopenia following Radical Cystectomy: Results of a Prospective Randomized Controlled Trial

We designed a prospective randomized controlled pilot trial to investigate the effects of an enriched oral nutrition supplement (ONS) on body composition and clinical outcomes following radical cystectomy (RC).
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Diabetic bladder dysfunction: A review

Urology (Gold Journal) In Press - Sat, 10/20/2018 - 00:00
Diabetic bladder dysfunction (DBD) affects almost half of all diabetic patients, making it one of the most common complications of diabetes mellitus. The clinical presentation of DBD can be varied and may be extremely bothersome to patients, negatively impacting their quality of life. Despite this, it remains under-studied and under-represented in the medical literature. This review summarizes the current literature on pathophysiology, clinical presentation, urodynamic findings, evaluation and management.
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REPLY TO LETTER-TO-THE-EDITOR: "CONCERNS ABOUT THE USE OF A FREE GRAFT DURING YORK-MASON INTERVENTION"

Urology (Gold Journal) In Press - Wed, 10/17/2018 - 00:00
While we recognize the thoughtful nature of this critique regarding the use of interposing fat grafts during the Modified York Mason procedure, we disagree with the concept that aberrant functionality or healing results. On the contrary, urinary and fecal streams are individually repaired to completion—the fat graft then is placed between the water-tight suture lines as a finalizing barrier. We reject the notion that interposing fat in this manner creates anatomic distortion of any physiologic significance.
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Estimating Minimally Important Differences for the Bladder Cancer Index Using Distribution- and Anchor-Based Approaches

The Bladder Cancer Index is a validated condition-specific health questionnaire assessing urinary, bowel and sexual function and quality of life among bladder cancer patients. We aimed to establish minimally important difference score thresholds that signal clinical importance.
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Can you take too much magnesium?

MedicalNewsToday - Tue, 10/16/2018 - 14:00
Magnesium is essential for health, but taking too much can cause problems, including digestive issues, lethargy, and an irregular heartbeat. In rare cases, an overdose can be fatal. Learn more here.
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Concurrent radiotherapy and panitumumab after lymph node dissection and induction chemotherapy for invasive bladder cancer

In this prospective study we evaluated safety and efficacy of concurrent radiotherapy and panitumumab following neoadjuvant/induction chemotherapy (ICT) and pelvic lymph node dissection (PLND) as a bladder preserving therapy for invasive bladder cancer (BC).
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Robotic-assisted radical cystectomy vs open radical cystectomy: systematic review and meta-analysis

To perform an updated systematic review and meta-analysis evaluating patient important outcomes for patients undergoing robot-assisted radical cystectomy (RARC) and open radical cystectomy (ORC).
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