Urology News Feeds

A Novel Calculator for Estimating Prostate Volume in Daily Urology Services.

Urology (Gold Journal) In Press - Mon, 05/07/2018 - 00:00
To develop a simple prostate volume (PV) calculator which can aid in managing patients with lower urinary tract symptoms (LUTS) secondary to benign prostatic enlargement at daily urology services in developing Asian countries.
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Reoperation Rates and Mortality after Transurethral and Open Prostatectomy in a Long-Term Nation-Wide Analysis: Have We Improved Over a Decade?

Urology (Gold Journal) In Press - Fri, 05/04/2018 - 00:00
To assess long-term re-operation rates and mortality after transurethral resection of the prostate (TURP) and open prostatectomy (PE) as therapy for lower urinary tract symptoms (LUTS) due to benign prostatic enlargement (BPE).
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Reply

Urology (Gold Journal) In Press - Fri, 05/04/2018 - 00:00
In this Editorial Comment accompanying our manuscript, the authors highlight the complexity inherent in understanding the effect of Accountable Care Organizations (ACOs) on urologic care. Particularly, they focus on the under-representation of urologists in ACOs. They also discuss the interaction between the uncertainty surrounding the benefits of prostate-specific antigen (PSA) screening in a population and ACO policies.
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Editorial Comment

Urology (Gold Journal) In Press - Fri, 05/04/2018 - 00:00
Accountable Care Organizations (ACOs) have been cited in specialist and lay media as a possible panacea for our healthcare system's woes. Enacted as part of the 2010 Affordable Care Act, ACOs were designed by the Center for Medicare and Medicaid Services (CMS) in pursuit of the “triple aim” of healthcare reform: higher quality, improved population health, and lower cost. The ACO payment model centers around the delivery of primary care. Groups of physicians, hospitals, and care networks assume responsibility for populations of Medicare beneficiaries.
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Validation of PI-RADS version 2 for the detection of prostate cancer

The second version of the Prostate Imaging Reporting and Data System (PI-RADSv2) was introduced in 2015 to standardize the interpretation and reporting of multiparametric prostate magnetic resonance imaging (mpMRI). Recently, low cancer detection rates (CDR) for PI-RADSv2 category 4 lesions were reported. Therefore the aim of the study was to evaluate the CDR of PI-RADSv2 in a large prospective cohort.
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Multiparametric-MRI/Ultrasound fusion prostate biopsy: are two biopsy cores per MRI-Lesion required?

For multiparametric MRI/Ultrasound fusion prostate biopsy (FUSBx) the number of taken biopsy cores is arbitrary established by urologists. Moreover, general consensus on the number of biopsy cores to be obtained from a single MRI-lesion is lacking. Therefore, we aimed to evaluate the feasibility of obtaining only one biopsy core per MRI-lesion.
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Acupuncture for chronic prostatitis/chronic pelvic pain syndrome: a randomized, sham acupuncture-controlled trial

To investigate the effectiveness of acupuncture for patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).
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Regulation of the Antioxidant-Response by MyoD Transcriptional Coactivator in Castration-Resistant Prostate Cancer Cells

Urology (Gold Journal) In Press - Thu, 05/03/2018 - 00:00
To reveal the potential role of the basic helix-loop-helix myogenic transcription regulator MyoD in the regulation of of castration-resistant prostate cancer (CRPC).
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The Role of Imaging in Prostate Cancer Care Pathway: Novel Approaches to Urologic Management Challenges Along Ten Imaging Touch Points

Urology (Gold Journal) In Press - Thu, 05/03/2018 - 00:00
We map out a typical prostate cancer care pathway through discussion of updates on modern imaging. Multiparametric MRI (mpMRI) is the most sensitive and specific imaging tool for diagnosis and local staging, transrectal ultrasound remains the most widely used technique for prostate biopsy guidance, CT and bone scan are useful in initial staging and recurrence detection. Novel imaging techniques in ultrasound elastography and mpMRI allow for increased lesion detection sensitivity and have the potential to enhance biopsy, while the development of new PET radiotracers has great promise for improved detection of local and metastatic disease in patients with biochemical recurrence.
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Magnet before the Needle: Commentary on MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis (PRECISION Trial)

Urology (Gold Journal) In Press - Thu, 05/03/2018 - 00:00
Systematic transrectal ultrasound (TRUS)-guided prostate biopsy has been the standard of care for the diagnosis of prostate cancer for many decades.1 In recent years the utility of magnetic resonance imaging (MRI) for targeted biopsy of prostate cancer has been on the rise with the aim of detecting clinically significant cancers while avoiding overdetection of cancers that do not require treatment.2
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Androgen Receptor–Targeted Treatments for Prostate Cancer: 35 Years’ Progress with Antiandrogens

Antiandrogens inhibit the androgen receptor (AR) and play an important role in the treatment of prostate cancer (PC). This review provides a historical perspective on the development and clinical benefit of antiandrogens in the treatment of PC.
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Bladder cancer survival in men using 5-alpha-reductase inhibitors

Androgens may have a role in bladder carcinogenesis. We studied whether use of 5-alpha-reductase inhibitors (5-ARIs) associates with bladder cancer (BCa)-specific mortality in a population-based cohort of men with BCa.
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Multi-institutional Outcomes of Endoscopic Management of Stricture Recurrence after Bulbar Urethroplasty

Approximately 10-20% of patients will have a recurrence after urethroplasty. Initial management of these recurrences is often with urethral dilation (UD) or direct vision internal urethrotomy (DVIU). In the current study, we describe outcomes of endoscopic management of stricture recurrence after bulbar urethroplasty.
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Menopause and Risk of Kidney Stones

Metabolic changes due to menopause may alter urine composition and kidney stone risk but results from prior work on this association have been mixed. We examined menopause and risk of incident kidney stones and changes in 24-hour urine composition in the Nurses’ Health Study II.
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Impact of Host Factors on Robotic Partial Nephrectomy Outcomes: Comprehensive Systematic Review and Meta-analysis

Host factors (tumor size/complexity, patient comorbidities) impact outcomes of robotic partial nephrectomy (RPN). We report a comprehensive systematic review and meta-analysis to critically evaluate impact of host factors on operative, peri-operative, functional, oncological and survival outcomes of RPN.
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Long-term outcomes after deferred radical prostatectomy in men initially managed by active surveillance

To determine the long-term outcomes after deferred radical prostatectomy.
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Sexual function in a nationwide cohort of 2260 testicular cancer survivors after 17 years follow-up

Evidence on the long-term impact of testicular cancer (TC) treatment on sexual function is not clear. The aim was to estimate the effect of TC treatment on the risk of sexual dysfunction in long-term testicular cancer survivors.
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Mental Health, Sleep, and Physical Function in Treatment-Seeking Women With Urinary Incontinence

To examine how mental health measures, sleep, and physical function are associated with presence and type of urinary incontinence (UI) and severity in women seeking treatment for lower urinary tract symptoms (LUTS).
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Priapism Throughout the Ages.

Urology (Gold Journal) In Press - Wed, 05/02/2018 - 00:00
Long-lasting penile erections are closely associated with the god Priapus. He was regarded as the son of Dionysus, god of the vine, and Aphrodite, goddess of beauty. When Aphrodite was pregnant, the story was that her mother Hera was jealous, had put her hands on the belly of her daughter and pronounced a curse. As a result Aphrodite gave birth to Priapus, a misshapen dwarf with a large erect penis(1), who as a result was subjected to ridicule and assumed to lack intelligence.(2) Since antiquity, long-lasting erections have been the object of scientific interest.
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Genital Lichen Sclerosus Et Atrophicus: A Benign Skin Disorder with Malignant Aftermath

Urology (Gold Journal) In Press - Wed, 05/02/2018 - 00:00
Genital lichen sclerosus et atrophicus is an uncommon genital dermatosis. Its resemblance to vitiligo especially during the earlier stages leads to delay in its diagnosis. Apart from the common complications such as meatal stenosis, balanoposthitis, phimosis and painful erections, squamous cell carcinoma (SCC) is a rare but ominous complication of genital LSA. Herein, we present a case of long standing penile LSA complicated by SCC stressing upon the requirement of early diagnosis and management of LSA.
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