Urology News Feeds

Re: Near-Infrared Intraoperative Molecular Imaging Can Identify Metastatic Lymph Nodes in Prostate Cancer

L. Xia, R. Zeh, J. Mizelle, A. Newton, J. Predina, S. Nie, S. Singhal and T. J. Guzzo
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Re: MYC Activation Cooperates with Vhl and Ink4a/Arf Loss to Induce Clear Cell Renal Cell Carcinoma

S. T. Bailey, A. M. Smith, J. Kardos, S. E. Wobker, H. L. Wilson, B. Krishnan, R. Saito, H. J. Lee, J. Zhang, S. C. Eaton, L. A. Williams, U. Manocha, D. J. Peters, X. Pan, T. J. Carroll, D. W. Felsher, V. Walter, Q. Zhang, J. S. Parker, J. J. Yeh, R. A. Moffitt, J. Y. Leung and W. Y. Kim
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Re: Selective Depletion of Uropathogenic E. coli from the Gut by a FimH Antagonist

C. N. Spaulding, R. D. Klein, S. Ruer, A. L. Kau, H. L. Schreiber, Z. T. Cusumano, K. W. Dodson, J. S. Pinkner, D. H. Fremont, J. W. Janetka, H. Remaut, J. I. Gordon and S. J. Hultgren
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Re: Estrogen Receptor β, a Regulator of Androgen Receptor Signaling in the Mouse Ventral Prostate

W. F. Wu, L. Maneix, J. Insunza, I. Nalvarte, P. Antonson, J. Kere, N. Y. Yu, V. Tohonen, S. Katayama, E. Einarsdottir, K. Krjutskov, Y. B. Dai, B. Huang, W. Su, M. Warner and J. Å. Gustafsson
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Re: Low Bone Density and Bisphosphonate Use and the Risk of Kidney Stones

M. Prochaska, E. Taylor, A. Vaidya and G. Curhan
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Re: Use of Medical Expulsive Therapy in Children: An Assessment of Nationwide Practice Patterns and Outcomes

J. S. Ellison, P. A. Merguerian, B. C. Fu, S. K. Holt, T. S. Lendvay, J. L. Gore and M. Shnorhavorian
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Re: Safety and Effectiveness of a Longer Focal Beam and Burst Duration in Ultrasonic Propulsion for Repositioning Urinary Stones and Fragments

K. M. Janssen, T. C. Brand, B. W. Cunitz, Y. N. Wang, J. C. Simon, F. Starr, H. D. Liggitt, J. Thiel, M. D. Sorensen, J. D. Harper, M. R. Bailey and B. Dunmire
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Autophagy, Apoptosis and Cell Proliferation in Exstrophy-Epispadias Complex

Urology (Gold Journal) In Press - Tue, 10/03/2017 - 00:00
To investigate the state of autophagy and its interactions with apoptosis and cell proliferation in patients who underwent successful early closure or delayed closure of exstrophy. They compared those outcomes with cell culture samples from patients with VUR as control.
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What Did We Find From Imaging Studies in Childhood UTI and Which Studies are Mandatory?

Urology (Gold Journal) In Press - Mon, 10/02/2017 - 00:00
To evaluate the imaging results of childhood UTI in our setting, and examine if it would be appropriate to apply the recent guideline changes regarding imaging studies as routine practice in Thailand.
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Reply by Authors

Since FDA clearance in October 2015, many HIFU treatments performed in the United States have been partial gland ablation for localized prostate cancer. We agree with the comment that focal therapy or partial gland ablation is an attractive option. If localized, even radio-recurrent prostate cancer could be treated in this manner.1
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Editorial Comment

Jones et al report their multi-institutional experience with whole gland HIFU ablation in the salvage setting after failed radiation therapy. This is timely, given the FDA approval of HIFU for prostate tissue ablation in 2015. Although the number of men with a combined negative biopsy and a PSA nadir of 0.5 ng/ml or less at 1 year is similar to those at European centers (references 1 and 7 in article), the PSA increases during further followup shed light on the uncertainty of expected posttreatment oncologic outcomes.
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Editorial Comment

Since FDA approval in 2015, HIFU has emerged as a potentially less invasive alternative to radical treatment in patients with localized prostate cancer in the United States. While outcomes of whole gland primary HIFU ablation have been reported,1 there is a paucity of data regarding the role of salvage HIFU. Furthermore, most available data were derived from European cohorts. In this study Jones et al assessed the efficacy and safety of whole gland HIFU ablation in 100 men with radio-recurrent prostate cancer treated at several centers across North America.
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Editorial Comment

This is an important study because sacral neuromodulation as a treatment modality in patients with OAB symptoms, and the long-term results and potential side effects are still questioned. When choosing between botulinum toxin injections and sacral neuromodulation as alternatives in the same group of patients, additional information is necessary on long-term efficacy and side effects. Also, in the ongoing debate on the cost-effectiveness of the 2 therapies data on long-term clinical efficacy are mandatory (reference 18 in article).
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A Novel Retrieval Technique for Ureteral Stents Under Ultrasound Guidance in Male Patients” by Taile Jing, Chao Zhang, and Lei Jiang accepted for publication http://dx.doi.org/10.1016/j.urology.2017.04.033

Urology (Gold Journal) In Press - Thu, 09/28/2017 - 00:00
We read your article with interest and would congratulate authors for describing a novel technique for removal of double-J stents in men under ultrasound guidance without cystoscopy. This technique was associated with less pain and may be especially suitable in older patients with hip osteoarthritis, osteoporosis or paralysis due to difficulty in making lithotomy position. However, we need some clarifications to better understand the article.
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Transplant Kidney Retrograde Ureteral Stent Placement and Exchange: Overcoming the Challenge

Urology (Gold Journal) In Press - Thu, 09/28/2017 - 00:00
To present a reliable technique for fluoroscopic controlled, large-bore, ureteral stent placement and exchange in transplant kidneys with persistent ureterovesical strictures.
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Trends in Prostate Cancer Incidence Rates and Prevalence of Prostate-Specific Antigen Screening by Socioeconomic Status and Regions in the US, 2004- 2013

It is unknown whether decreases in the prevalence of prostate-specific antigen (PSA) screening and prostate cancer incidence rates, following the US Preventive Service Task Force (USPSTF) recommendations against routine PSA, are similar across socioeconomic groups and US census regions.
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Use of Third Line Therapy for Overactive Bladder in a Practice with Multiple Subspecialty Providers: Are we doing enough?

Overactive bladder (OAB) impacts over 15% of the adult population. Compliance with medical treatment is low, due either to inadequate symptom control or intolerable side effects. Although third line therapies have improved the treatment of OAB, many patients do not receive optimal treatment. We hypothesize that the utilization of third line treatment is higher among female pelvic medicine and reconstructive surgery urologists and examine its use in our tertiary referral center.
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Re: Outcomes of Anastrozole in Oligozoospermic Hypoandrogenic Subfertile Men

O. Shoshany, N. Abhyankar, N. Mufarreh, G. Daniel and C. Niederberger
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