Urology News Feeds

The Efficacy and Safety of OnabotulinumtoxinA or Solifenacin Compared with Placebo in Solifenacin-Naïve Patients with Refractory Overactive Bladder: Results from a Multicenter, Randomized, Double-Blind, Phase 3b Trial

This double-blind, randomized study compared the efficacy/safety of onabotulinumtoxinA or solifenacin versus placebo in overactive bladder patients with urinary incontinence who had an inadequate response to/were intolerant of an anticholinergic. A post-hoc analysis compared effects of onabotulinumtoxinA versus solifenacin.
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Editorial Comment

The authors have assembled data supporting a hypothesis, and a widely held perception among pediatric urologists, that the volume of oncologic surgeries being done by pediatric urologists is quite low. This finding is not a surprise. There are a lot and surgeons and not many tumors. The cited studies (references 3 to 5 in article), along with a more recent report,1 suggest that there are at most small differences in outcomes between high and low volume hospitals. There do appear to be significant differences in outcomes between Children’s Oncology Group and non-Children’s Oncology Group affiliated hospitals.
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Editorial Comment

In 2014 the Pediatric Urologic Oncology Working Group emailed a survey to Society for Pediatric Urology members concerning participation in oncology care. Of 200 responding pediatric urologists 22% denied performing cancer surgeries, in contrast to the 53.4% noted in the present study. While 25% of survey respondents claimed more than 6 surgeries, this study found that 4 cases comprise the 95th percentile for oncology volume.1 This discrepancy suggests recall bias by survey participants or sample biases within the case logs.
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Mayo Adhesive Probability Score Is an Independent Computed Tomography Scan Predictor of Adherent Perinephric Fat in Open Partial Nephrectomy

Urology (Gold Journal) In Press - Wed, 02/01/2017 - 00:00
To evaluate predictive radiological elements for adherent perinephric fat (APF) and the Mayo adhesive probability (MAP) score in the setting of open partial nephrectomy, and to assess their reproducibility.
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