Urology News Feeds

Effects of withdrawing alpha-1 blocker from the combination therapy with alpha-1 blocker and 5-alpha-reductase inhibitor in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: A prospective and comparative trial using...

To compare the effects on lower urinary tract symptoms (LUTS) and bladder outlet obstruction between combination therapy with α1 blocker and 5α-reductase inhibitor and a switch to 5α-reductase inhibitor monotherapy, and determine the factors influencing changes in LUTS after α1 blocker withdrawal.
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Fluid overload linked to premature death in patients on dialysis

MedicalNewsToday - Mon, 05/08/2017 - 02:00
New research indicates that sustained fluid overload - when there is too much fluid in the blood - may increase the risk of early death in kidney failure patients on hemodialysis.
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Renal arterial mycotic aneurysm after kidney transplantation

Urology (Gold Journal) In Press - Mon, 05/08/2017 - 00:00
Mycotic aneurysm is a rare condition mostly attributable to Candida or Aspergillus species. About 20 cases of Candida-related arteritis have been reported in kidney transplant patients. Herein, we report the case of a 40-year-old man who received a kidney from a deceased donor in whom an accidental digestive wound was made during organ retrieval. He presented with sudden anuria 47 days after renal transplantation revealing a large mycotic aneurysm of the kidney graft renal artery. Organs derived from donors in whom a digestive breach is noticed should be used with caution.
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Use of Bipedicled Dorsal Penile Flap with Z Release Incision: a New Option in Redo Hypospadias Surgery

Urology (Gold Journal) In Press - Mon, 05/08/2017 - 00:00
To solve the challenge in redo hypospadias surgery; we tried the use of bipedicled dorsal penile flap with Z release incision in failed hypospadias cases and reported the outcome.
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Penile Fracture Following a Fall in a Seven Year Old Male

Urology (Gold Journal) In Press - Mon, 05/08/2017 - 00:00
We report a rare case of isolated penile fracture in a prepubescent male caused by an accidental fall. The patient presented with swelling and ecchymosis on the base of the penis and along the penile shaft. A flexible cystoscopy was performed which did not reveal any concomitant urethral injury. The penis was degloved and the corporal tear was closed with absorbable suture. Due to the location of the injury, ventral mobilization of the urethra was required. The pathophysiology of penile fracture as well as the diagnosis and management of this rare injury are discussed in this report.
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Up and Away: Five Decades of Urologic Investigation in Microgravity

Urology (Gold Journal) In Press - Mon, 05/08/2017 - 00:00
A renewed global interest in manned space-exploration has emerged, propelled by the challenge of reaching a new frontier: travel to the Red Planet, Mars. As the physiologic changes induced by microgravity bear direct relevance to the safety and viability of these goals, we provide a historical narrative of the urological investigations in space. We review the significant contributions to the understanding of the urologic consequences associated with exposure to microgravity, considerations for prolonged missions, and forward-looking efforts to manage emergent conditions remotely.
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Editorial Comment

Urology (Gold Journal) In Press - Mon, 05/08/2017 - 00:00
Urodynamics (UDS) is a well-established tool for the evaluation of lower urinary tract symptoms (LUTS) and has been of great importance to the understanding of the pathophysiology of LUT dysfunction. It has been used to identify factors contributing to LUTS and to predict the outcomes of therapeutic interventions. Because high quality evidence-based is lacking to assist the clinician in the proper use of UDS in different conditions, its value is often debated. In addition, other factors come into play regarding the indication of UDS, such as the invasiveness and potential complications of the test and its impact on health economic costs.
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Differential Expression Of Pd-L1 In High Grade T1 Vs Muscle Invasive Bladder Carcinoma And Its Prognostic Implications

PD-1 ligand (PD-L1) is expressed on both tumor cells (TCs) and tumor immune cell infiltrates (TIMC). In metastatic bladder cancer, increased TIMC PD-L1 positivity (PD-L1+) was correlated with better overall survival, however, in high grade T1 bladder tumors (HGT1) PD-L1+ on TCs and TIMCs, and correlation with outcome or pathological features remain unknown.
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Variation in Use of Prostate Biopsy Following Changes in Prostate Cancer Screening Guidelines

Prostate biopsy rates have paralleled declining PSA screening rates since 2012. We hypothesized that biopsy rates and change in rates since 2012 would vary considerably across hospital referral regions.
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New blood test predicts who will benefit from targeted prostate cancer treatments

MedicalNewsToday - Fri, 05/05/2017 - 02:00
A new blood test could predict which men with advanced prostate cancer will respond to new targeted treatments for the disease.
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Erectile Dysfunction in Wistar Audiogenic Rats (WAR) is Associated with Increased Cavernosal Contraction and Decreased nNOS Protein Expression

Urology (Gold Journal) In Press - Fri, 05/05/2017 - 00:00
To test the hypothesis that naïve Wistar audiogenic rats (WAR) display ED, which is associated with increased sympathetic-mediated contractile tone and/or decreased NO-mediated relaxation responses of the cavernous tissue.
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Self-Reported Clinical Meaningfulness Early in the Treatment Course Predicts Objective Outcomes in Men Undergoing Collagenase Clostridium Histolyticum Injections for Peyronie's Disease

Urology (Gold Journal) In Press - Fri, 05/05/2017 - 00:00
To compare perceived meaningfulness early in the course of collagenase clostridium histolyticum (CCH) with final outcomes in order to evaluate its utility as a predictor of efficacy.
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Robotic Radical Left Nephrectomy with IVC Level III Thrombectomy

Urology (Gold Journal) In Press - Fri, 05/05/2017 - 00:00
Introduction and ObjectiveRobotic management of a left sided inferior vena cava (IVC) tumor thrombus is challenging due to the superior mesenteric artery crossing the left renal vein which requires robotic docking from the left, for dissection of the left kidney followed by repositioning and re-docking the robot from the right side for dissection of the right renal vein, distal and proximal IVC, and the remaining left renal vein insertion into the IVC. We present our robotic approach and technique to manage a large left renal tumor with IVC Level III thrombus.
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Percutaneous Management of Stone Containing Calyceal Diverticula: Associated Factors and Outcomes

We evaluated the outcomes of percutaneous treatment and metabolic evaluation of calyceal diverticula with associated stones.
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Independent Predictors of Stricture Recurrence Following Urethroplasty for Isolated Bulbar Urethral Strictures

To evaluate pre-operative risk factors associated with stricture recurrence in a large, homogenous series of bulbar urethroplasties.
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AUA Standard Operating Procedure for MRI of the Prostate

The purpose of this review is to summarize the available data about the clinical and economic effectiveness of MRI in the diagnosis and management of prostate cancer and to provide practical recommendations for the use of MRI in the screening, diagnosis, staging and surveillance of prostate cancer.
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Re: Operating Room Fires and Surgical Skin Preparation

E. L. Jones, D. M. Overbey, B. C. Chapman, T. S. Jones, S. A. Hilton, J. T. Moore and T. N. Robinson
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Re: Safety and Early Oncologic Effectiveness of Primary Robotic Retroperitoneal Lymph Node Dissection for Nonseminomatous Germ Cell Testicular Cancer

S. M. Pearce, S. Golan, M. A. Gorin, A. N. Luckenbaugh, S. B. Williams, J. F. Ward, J. S. Montgomery, K. S. Hafez, A. Z. Weizer, P. M. Pierorazio, M. E. Allaf and S. E. Eggener
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