Urology News Feeds

Re: Qualitative Exploration of the Patient Experience of Underactive Bladder

A. D. Uren, N. Cotterill, C. Harding, C. Hillary, C. Chapple, M. Klaver, D. Bongaerts, Z. Hakimi and P. Abrams
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Re: Value of an Immediate Intravesical Instillation of Mitomycin C in Patients with Non-Muscle-Invasive Bladder Cancer: A Prospective Multicentre Randomised Study in 2243 Patients

J. Bosschieter, J. A. Nieuwenhuijzen, T. van Ginkel, A. N. Vis, B. Witte, D. Newling, G. M. A. Beckers and R. J. A. V. Moorselaar
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Re: Neutrophil-to-Lymphocyte Ratio as a Bladder Cancer Biomarker: Assessing Prognostic and Predictive Value in SWOG 8710

E. Ojerholm, A. Smith, W. T. Hwang, B. C. Baumann, K. N. Tucker, S. P. Lerner, R. Mamtani, B. Boursi and J. P. Christodouleas
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Intravesical Electromotive Botulinum Toxin Type “A” Administration for Management of Urinary Incontinence Secondary to Neuropathic Detrusor Overactivity in Children: Long-Term Follow-up

Urology (Gold Journal) In Press - Fri, 12/08/2017 - 06:00
To investigate the long-term efficacy and success rate of intravesical electromotive botulinum toxin type A (BoNTA) “Dysport®” administration in myelomeningocele (MMC) patients who had urinary incontinence due to neuropathic detrusor overactivity (NDO).
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Remedies for ulcerative colitis constipation

MedicalNewsToday - Thu, 12/07/2017 - 08:00
Some people with ulcerative colitis experience frequent constipation. Learn about the treatment options, including magnesium and castor oil.
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Dual Pathology Causing Congenital Bladder Outlet Obstruction

Urology (Gold Journal) In Press - Thu, 12/07/2017 - 06:00
Anterior urethral syringocele is an uncommon congenital deformity characterised by cystic dilatation of bulbo-urethral gland ducts and is usually asymptomatic. We present a case on 4-day-old male neonate who presented with bilateral antenatal hydroureteronephrosis and renal impairment and found to have urethral syringocele and posterior urethral valves (PUV).
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Retained Bullet in the Kidney: Imaging and Conservative Management

Urology (Gold Journal) In Press - Thu, 12/07/2017 - 06:00
Renal gunshot wounds resulting in a grade IV injury (AAST) should be explored only if they involve the hilum or if there are signs of suspected renal pelvis or ureteral laceration, active haemorrhage, peritonitis or hemodynamically unstable patients.1 However, due to the paucity of cases reported in the literature, it is not clear what the best management of patients with a retained bullet is, which have been traditionally treated with surgical retrieval in other organs. We present the radiological findings and a clinical case summary of a patient with Grade IV kidney injury and retained bullet managed conservatively.
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Anatomical Control of Adenoma (Ancona) Technique: an Accurate Surgical Approach to Thulium Laser Enucleation of the Prostate

Urology (Gold Journal) In Press - Thu, 12/07/2017 - 06:00
To present our two-lobe technique of thulium laser transurethral enucleation of prostate. Transurethral resection of prostate and open prostatectomy (OP), have been traditionally considered the gold standard of benign prostatic enlargement (BPE) surgical treatment. Laser have been recently made available for BPE surgery, in order to minimize morbidity of traditional surgery1. In 2009 Bach introduced the use of thulium laser2, describing the 3-lobes technique, which overlaps OP but with a greater control of hemostasis3.
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Clinical Utility and Biologic implications of Phosphatase and Tensin Homolog (PTEN) and ETS-related Gene (ERG) in Prostate Cancer

Urology (Gold Journal) In Press - Thu, 12/07/2017 - 06:00
Phosphatase and Tensin Homolog (PTEN) and ETS-related Gene (ERG) mutations are commonly found in prostate cancer. Although mouse studies have demonstrated PTEN and ERG cooperatively interact during tumorigenesis, human studies examining these genes have been inconclusive. A systematic Pubmed search including original articles assessing the pathogenesis of PTEN and ERG in prostate cancer was performed. Studies examining ERG's prognostic significance have conflicting results. Studies examining PTEN and ERG simultaneously found these genes are likely to occur together but cooperative tumorigenesis functions have not been conclusively established.
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Impact of Comorbidities on Functional Recovery from Partial Nephrectomy

Preservation of parenchymal mass and ischemia type/duration can influence functional recovery after partial nephrectomy (PN). Some have hypothesized that relevant comorbidities may also impact nephron stability and functional recovery, but this has not been adequately investigated.
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Effect of music on outpatient urological procedures: A systematic review and meta-analysis from European section of Uro-technology (ESUT)

Music is a practical, cheap and harmless analgesic and anxiolytic. An increasing number of original studies have been performed investigating its potential application in urology. Our aim was to identify the effect of music on outpatient based urological procedures.
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Crowdsourcing Disease Biomarker Discovery Research; The IP4IC Study

Biomarker discovery is limited by readily assessable, cost efficient, human samples available in large numbers that represent the entire heterogeneity of the disease. We developed a novel active participation crowdsourcing method to develop a Bladder Permeability Defect Risk Score (BP-RS) based on non-invasive urinary cytokines to discriminate Interstitial cystitis/bladder pain syndrome (IC/BPS) with Hunner’s lesion (UIC) patients from controls and IC patients without Hunner’s lesions.
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Comparison of Pathological and Oncologic Outcomes in “Favorable Risk” GS 3+4 and Low Risk GS6 Prostate Cancer: Considerations for Active Surveillance

Recent NCCN guidelines report that patients with biopsy GS 3+4/GG2 but otherwise favorable features as active surveillance (AS) candidates. However, little is known about their long-term outcomes compared to low-risk GS6/GG1 group. This study aims to clarify the risk of adverse features and oncologic outcomes for surgically-treated favorable GG2 vs GG1 patients.
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Functional recovery, oncologic outcomes and postoperative complications 12 months following robot-assisted radical prostatectomy: follow-up of an evidence-based analysis comparing the Retzius-sparing and standard approaches

To report 1-year update of functional (urinary and sexual) recovery, oncological outcomes, and postoperative complications in patients who completed a randomized controlled trial comparing posterior (Retzius-sparing) with anterior robot-assisted radical prostatectomy (RARP).
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Radical Nephrectomy With or Without Lymph Node Dissection for High-Risk Non-Metastatic Renal Cell Carcinoma: A Multi-Institutional Analysis

LND may benefit patients at increased risk of lymph node (LN) metastases from renal cell carcinoma (RCC). We therefore evaluated the association of LND with survival among high-risk patients undergoing radical nephrectomy (RN) for RCC.
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A Multi-institutional Prospective Trial in the Veterans Affairs Health System confirms the 4Kscore maintains its Predictive value among African American Men

The 4Kscore test accurately detects aggressive prostate cancer and reduces unnecessary biopsies, however, its performance in African American (AA) men is unknown. This study assessed the performance of the 4Kscore test in a cohort of men with a large AA representation.
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Lymphatic drainage from renal tumors in vivo: a prospective sentinel node study using SPECT/CT imaging

Lymphatic drainage from renal tumors is unpredictable and in vivo drainage studies of primary lymphatic landing sites may reveal the variability and dynamics of lymphatic connections. The purpose of this study was to investigate the lymphatic drainage pattern from renal tumors in vivo with SPECT/CT imaging after intra-tumoral radiotracer injection.
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