Urology News Feeds
Re: Cognitive Function in Patients with Prostate Cancer Receiving Luteinizing Hormone-Releasing Hormone Analogues: A Prospective, Observational, Multicenter Study
J. Morote, Á. J. Tabernero, J. L. Á. Ossorio, J. P. Ciria, J. L. Domínguez-Escrig, F. Vázquez, J. Angulo, F. J. López, R. de La Iglesia and J. Romero; ANAMEM Investigator Group
J. Jaber, S. Kocherov, L. Chertin, A. Farkas and B. Chertin
L. Örtqvist, M. Andersson, A. Strandqvist, A. Nordenström, L. Frisén, G. Holmdahl and A. Nordenskjöld
Re: Two-Stage Graft Urethroplasty for Proximal and Complicated Hypospadias in Children: A Retrospective Study
A. Faure, A. Bouty, Y. L. Nyo, M. O’Brien and Y. Heloury
W. Snodgrass and N. Bush
C. M. Fronczak and C. A. Villanueva
The consequences of radical orchiectomy in a young man are substantial, including psychological distress,1 reduced fertility and an increased risk of testicular failure.2 If the testis could be preserved in the 5% to 10% cases of benign lesions which present as a testicular mass, these consequences may be avoided. Unfortunately it is not yet possible to accurately diagnose benign masses preoperatively.
Once again Germany is leading voice in the field of testis sparing surgery for small lesions. This group formulated guidelines to help treat patients with small lesions that have a relatively high chance of being benign.
This study is important as many have placed their faith in MRI to avoid unnecessary prostate biopsies. Perhaps it was misplaced? Further, increasingly we are learning that MRI is significantly operator dependent, adding yet another variable to the use of this technology to avoid biopsy. So how do we incorporate the results of the PROMIS trial (reference 8 in article) and this study, which are really from centers of experience, if not excellence?
The comments adequately indicate the scenario. Currently many patients may require TEOMG, particularly patients who refuse mouth graft harvesting, patients with a congenitally small mouth, ie the Chinese population,1 patients with a small mouth opening due to previous trauma or surgery in the mandibular arch, patients requiring large bilateral graft harvesting, which represents a significant predictor of patient dissatisfaction (reference 24 in article), patients requiring large rectangular graft harvesting for 2-stage urethroplasty and patients with recurrent urethral stricture who have already undergone graft harvesting form each cheek.
Anterior urethral strictures present a reconstructive challenge. Various techniques have been developed to improve the chances of long-term urethral patency, including oral mucosa grafts. Although harvesting buccal mucosa is an expedient technique which is cost-effective and done easily by reconstructive urologists, it is not a perfect solution and complications can arise.
For nontraumatic and longer strictures of the anterior urethra the role of genital skin flaps has decreased slowly in the last 20 years. Flaps are now reserved for complex and post-radiation strictures.1 Today oral mucosal grafts have gained popularity as the material of choice for augmentation in most cases.
Retrograde Ureteral Catheterization: a Possible New Treatment for Renal Fungal Balls in Very-Low-Birth-Weight Infants
Invasive candidiasis is a serious pathogen of late-onset sepsis in very-low-birth- weight (VLBW) infants. Kidney is the most common organ involved and it causes morbidity and mortality, especially when fungal balls are formed. We report a 34-day-old female infant (28 weeks, 1152 gm) with systemic fungal infection complicated obstructive uropathy. On sonography, the fungal balls filled the entire pelvis without hydronephrosis. Percutaneous nephrostomy was not feasible. In addition to systemic antifungals, we successfully performed cystoscopy-assisted retrograde ureteral catheterization (RUC) to decompress the pelvis, which also provided a route for local amphotericin B irrigation to achieve therapeutic concentration without nephrotoxicity.
We agree with the comments that capturing patient reported HRQOL is paramount in BC research and care. We believe that the BUSS is unique because in 10 questions it explores the most vital issues to patients and is written in language appropriate for anyone with the disease. Thinking beyond pelvic toxicity, we created the BUSS as a holistic measure, focusing on global HRQOL.
Oncology patients are confronted with physical and psychological consequences from the disease and treatment, which ultimately have a significant impact on overall HRQOL. In recent years PROs have increasingly had integral roles in clinical trials, quality of care assessment and comparative effectiveness research. Accurately assessing HRQOL in patients with BC is challenging due to the disparate courses and treatments in such patients (ie transurethral resection, intravesical therapy, cystectomy, chemotherapy and radiation therapy).
Re: Clinical and Patient-Reported Outcomes of 1-Sided Anterior Urethroplasty for Long-Segment or Panurethral Strictures
J. Spencer, S. Blakely, M. Daugherty, J. C. Angulo, F. Martins, K. Venkatesan and D. Nikolavsky
N. Thirumavalavan, M. S. Gross and R. Munarriz
X. Serra-Aracil, M. Labro-Ciurans, L. Mora-Lopez, J. Munoz-Rodriguez, R. Martos-Calvo, J. Prats-Lopez and S. Navarro-Soto
N. Johnsen, D. F. Penson, W. S. Reynolds, D. F. Milam, R. R. Dmochowski and M. R. Kaufman