Urology News Feeds

Re: Sexual Function and Quality of Life before and after Penile Prosthesis Implantation following Radial Forearm Flap Phalloplasty

E. E. Young, D. Friedlander, K. Lue, U. A. Anele, J. L. Khurgin, T. J. Bivalacqua, A. L. Burnett, R. J. Redett and J. P. Gearhart
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Re: Association between Radiation Therapy, Surgery, or Observation for Localized Prostate Cancer and Patient-Reported Outcomes after 3 Years

D. A. Barocas, J. Alvarez, M. J. Resnick, T. Koyama, K. E. Hoffman, M. D. Tyson, R. Conwill, D. McCollum, M. R. Cooperberg, M. Goodman, S. Greenfield, A. S. Hamilton, M. Hashibe, S. H. Kaplan, L. E. Paddock, A. M. Stroup, X. C. Wu and D. F. Penson
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Re: Multicenter Investigation of the Micro-Organisms Involved in Penile Prosthesis Infection: An Analysis of the Efficacy of the AUA and EAU Guidelines for Penile Prosthesis Prophylaxis

Penile prosthesis infections remain challenging despite advancements in surgical technique, device improvements and adoption of antibiotic prophylaxis guidelines. The authors of this retrospective, institutional review board exempt, multi-institutional study from 25 centers reviewed intraoperative cultures obtained at explantation or Mulcahy salvage of infected 3-piece IPPs. Antibiotic use was recorded at implantation, admission for infection and explantation or salvage surgery. Cultures were obtained from purulent material in the implant space and from the biofilm on the device.
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Re: Multicenter Investigation of the Micro-Organisms Involved in Penile Prosthesis Infection: An Analysis of the Efficacy of the AUA and EAU Guidelines for Penile Prosthesis Prophylaxis

M. S. Gross, E. A. Phillips, R. J. Carrasquillo, A. Thornton, J. M. Greenfield, L. A. Levine, J. P. Alukal, W. P. Conners, III, S. Glina, C. Tanrikut, S. C. Honig, E. F. Becher, N. E. Bennett, R. Wang, P. E. Perito, P. J. Stahl, M. Rosselló Gayá, M. Rosselló Barbará, J. D. Cedeno, E. L. Gheiler, O. Kalejaiye, D. J. Ralph, T. S. Köhler, D. S. Stember, R. E. Carrion, P. P. Maria, W. O. Brant, M. W. Bickell, B. B. Garber, M. Pineda, A. L. Burnett, II, J. F. Eid, G. D. Henry and R. M. Munarriz
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Re: Preoperative Urine Culture Results Correlate Poorly with Bacteriology of Urologic Prosthetic Device Infections

N. L. Kavoussi, J. A. Siegel, B. R. Viers, T. J. Pagliara, M. D. Hofer, B. H. Cordon, N. Shakir, J. M. Scott and A. F. Morey
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Re: A Prospective Longitudinal Survey of Erectile Function Status in Symptomatic Benign Prostatic Hyperplasia Patients Treated with Dutasteride

T. Maeda, E. Kikuchi, M. Hasegawa, T. Ando, M. Matsushima, K. Yuge, Y. Ito, A. Miyajima and M. Oya
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Re: Quality of Life in Patients with Lower Urinary Tract Symptoms Associated with BPH: Change over Time in Real-Life Practice According to Treatment—The QUALIPROST Study

A. Alcaraz, J. Carballido-Rodríguez, M. Unda-Urzaiz, R. Medina-López, J. L. Ruiz-Cerdá, F. Rodríguez-Rubio, D. García-Rojo, F. J. Brenes-Bermúdez, J. M. Cózar-Olmo, V. Baena-González and J. Manasanch
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Re: Impact of Combination Therapy 5-Alpha Reductase Inhibitors (5-ARI) plus Alpha-Blockers (AB) on Erectile Dysfunction and Decrease of Libido in Patients with LUTS/BPH: A Systematic Review with Meta-Analysis

V. Favilla, G. I. Russo, S. Privitera, T. Castelli, R. Giardina, A. E. Calogero, R. A. Condorelli, S. La Vignera, S. Cimino and G. Morgia
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Re: Outcomes of Artificial Urinary Sphincter Placement in Octogenarians

M. J. Ziegelmann, B. J. Linder, M. E. Rivera, B. R. Viers, L. J. Rangel and D. S. Elliott
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Prostate Cancer Local Recurrence Detected with Both F-Fluciclovine and PSMA-Targeted F-DCFPyL PET/CT

Urology (Gold Journal) In Press - Mon, 06/19/2017 - 00:00
We present the case of a 79-year-old man with an elevated post-prostatectomy PSA level who was sequentially imaged with PET/CT using 18F-fluciclovine followed by PSMA-targeted 18F-DCFPyL. Although both imaging tests successfully identified the same pelvic recurrence, each radiotracer had its relative merits. This case highlights the differences between these two PET radiotracers which are increasingly being used to image men with recurrent prostate cancer.
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Microsurgically assisted inguinal hernia repair and simultaneous male fertility procedures: Rationale, technique and outcomes

Inguinal herniorrhaphy is the most common general surgical procedure. It is associated with frequent complications such as recurrence (1.9% with mesh), post-operative hematoma (4.5%), reduced sensation (0 – 42.8%), chronic post-operative pain (5.1%), vasal injury (0.1 – 0.53%) and infection (3 – 6%)1–5. Drawing on our experience utilizing the operating microscope for varicocelectomy, vasectomy reversal and repair of iatrogenic vasal obstruction from hernia repair, we employed it for inguinal hernia repair.
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The Over Time Conditional Survival of Intravesical Recurrence in Upper Tract Urothelial Carcinoma

Since a conditional survival (CS) analysis provides better estimates of survival times at each follow-up, we aimed to assess changes in conditional intravesical recurrence-free survival (IVRFS) rates after radical nephroureterectomy (RNU) and how the impact of well-known risk factors evolves over time, particularly in localized upper tract urothelial carcinoma (UTUC) patients.
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Genomic Tests Should be Used to Help Guide Treatment of Prostate Cancer

Genomic profiling brings the promise of personalized risk prediction in men with prostate cancer facing treatment decisions. The 3 commercially available genomic signatures (Prolaris®, Oncotype DX® and Decipher® test) are considered to be useful resources for patients deciding between immediate treatment versus active surveillance as well as for those who require adjuvant radiation after radical prostatectomy (RP).1 Similar markers used for decision making about breast cancer have been subjected to much more rigorous scientific investigation in order to provide the highest level of evidence to justify their use.
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Genomic Tests Should be Used to Help Guide Treatment of Prostate Cancer

Prostate cancer is a heterogeneous disease. This heterogeneity exists on many levels encompassing the spectrum from clinical presentation to disease trajectory as well as molecular features to treatment response. Lack of uniformity in these and other facets persistently confounds the most elementary of clinical decisions facing urologists today, which is how to best treat a man diagnosed with clinically localized prostate cancer. While the question may be simple, the answer has proven to be complex.
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Percutaneous Nephrolithotomy Puncture and Tract Dilation: Evidence on the Safety of Approaches to the Infundibulum of the Middle Renal Calyx

Urology (Gold Journal) In Press - Fri, 06/16/2017 - 00:00
To investigate the anatomical relations of the papillary, infundibular and pelvic approach to percutaneous nephrolithotomy (PCNL) and evaluate the amount of vascularization at the respective sites.
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Editorial Comment

As we become more experienced and more comfortable with AS there is a natural tendency to expand the indications to men with intermediate risk disease. In this series from Cleveland Clinic the authors included patients at intermediate risk in a AS cohort. The protocol was not standardized. Tests such as prostate cancer antigen 3 and tumor genomics were increasingly used and confirmatory biopsy rates decreased with time. The patients at intermediate risk were added later and represented older men with lower volume Gleason 7 cancer and shorter followup.
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Intermediate Risk Prostate Cancer and Active Surveillance: Maximize Utilization while Minimizing Failure

Financial interest and/or other relationship with Sanofi-Aventis, Janssen and Profound.
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Re: Irreversible Electroporation of Small Renal Masses: Suboptimal Oncologic Efficacy in an Early Series

N. E. Canvasser, I. Sorokin, A. H. Lay, M. S. Morgan, A. Ozayar, C. Trimmer and J. A. Cadeddu
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