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Editorial Comment

This retrospective study of almost 700,000 Navy personnel in a 10-year period examined stone disease among pilots. The issue deserves special attention. In civilians stones cause morbidity and pain (reference 3 in article) but among military pilots stones can be career and life altering. Currently Navy pilots can be grounded for even asymptomatic stones. This implies significant military costs and exposure of young, healthy individuals to potentially unnecessary surgery (reference 22 in article).
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Role of Preoperative Testicular Shear-Wave Elastography in Predicting Improvement of Semen Parameters after Varicocelectomy for Male Patients with Primary Infertility

Urology (Gold Journal) In Press - Wed, 04/26/2017 - 00:00
To evaluate the role of preoperative testicular Shear wave elastography in prediction of improvement of semen analysis parameters after subinguinal microsurgical varicocele ligation in patients with primary infertility and clinically detectable varicocele.
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Dietary Sodium Restriction Reduces Nocturnal Urine Volume and Nocturnal Polyuria Index in Renal Allograft Recipients with Nocturnal Polyuria

Urology (Gold Journal) In Press - Wed, 04/26/2017 - 00:00
To investigate whether sodium restriction alters nocturnal urine volume (NUV) and the ratio of NUV to 24-hr urine of renal allograft recipients (RAR).
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AZFa Microdeletions: Occurrence in Chinese Infertile Males and Novel Deletions Revealed by Semiconductor Sequencing

Urology (Gold Journal) In Press - Wed, 04/26/2017 - 00:00
To evaluate the frequency of AZFa microdeletions among infertile males, and establish a new high-throughput sequencing method to detect novel deletion types.
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Long-Term Health Related Quality of Life Outcomes Following Radical Cystectomy

Urology (Gold Journal) In Press - Wed, 04/26/2017 - 00:00
To evaluate the long-term (>5 years) health-related quality of life outcomes following radical cystectomy, comparing Indiana pouch (IP), neobladder (NB), and ileal conduit (IC).
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Does the surgeon’s experience affect operation times, adverse events and continence outcomes in HoLEP? A review of over 1000 cases

Holmium Laser Enucleation of the Prostate (HoLEP) has become an increasingly common surgical therapy for benign prostate hyperplasia. However, the relationship between the surgeon’s experience and surgical outcomes have not yet been fully investigated. In this study, we investigated how the surgeons’ experience in HoLEP affected operation times, adverse events and outcomes related to urination.
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Treatment of Non-Metastatic Muscle-Invasive Bladder Cancer: AUA/ASCO/ASTRO/SUO Guideline

This multi-disciplinary, evidence-based guideline for clinically non-metastatic muscle-invasive bladder cancer focuses on the evaluation, treatment, and surveillance of muscle-invasive bladder cancer guided toward curative intent.
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Testing urine for particular proteins could be key to preventing kidney transplant failure

MedicalNewsToday - Tue, 04/25/2017 - 02:00
Testing for molecular markers in the urine of kidney transplant patients could reveal whether the transplant is failing and why, according to research presented at the 27th European Congress of...
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Old Tools, Old Problems, New Solution: the Use of a Modified Cecil-Culp Concept in the Trauma Setting

Urology (Gold Journal) In Press - Tue, 04/25/2017 - 00:00
A 12-year-old boy sustained a close-range shotgun wound with buckshot to the penis and lower abdomen. The proximal two-thirds of the corpora cavernosa were obliterated, and the distal third was thrombosed. All dorsal penile skin was lost. The urethra remained intact. The patient underwent multiple debridements, allowing the wound to declare its borders. Employing the tissue transfer concept used by Cecil and Culp in hypospadias repairs, the penis was marsupialized onto the suprapubic area where it remained for 8 months.
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Physicians' Perceptions of Factors Influencing the Treatment Decision-Making Process for Men with Low-Risk Prostate Cancer

Urology (Gold Journal) In Press - Tue, 04/25/2017 - 00:00
To assess physicians' attitudes regarding multiple factors that may influence recommendations for AS vs. AT given the central role physicians play in the treatment-decision making process.
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Use of a 17-gene prognostic assay in contemporary urologic practice: results of an interim analysis in an observational cohort

Urology (Gold Journal) In Press - Tue, 04/25/2017 - 00:00
To study the impact of genomic testing in shared decision making for men with clinically low risk prostate cancer (PCa).
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Expanding Immunotherapy Options for Bladder Cancer

Urology (Gold Journal) In Press - Tue, 04/25/2017 - 00:00
KEYNOTE-045 was a phase 3 multicenter open-label randomized trial of the PD-1 inhibitor pembrolizumab versus second line chemotherapy in patients with advanced urothelial cancer. It included patients previously treated for advanced disease with a platinum-containing regimen as well as those who recurred within 12 months of receiving perioperative chemotherapy for muscle-invasive disease. To be eligible, patients had to have a good ECOG performance status (PS score of 0 or 1). Patients with an ECOG PS score of 2 were allowed only if they had none of the other three Bellmunt risk factors (hemoglobin under 10 g/dL, liver metastasis or last chemotherapy within the past 3 months) [1].
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Ointment Fistulography: Introducing a Novel Technique for Single or Multiple Urethrocutaneous Fistula Diagnosis after Hypospadias Surgery

Urology (Gold Journal) In Press - Tue, 04/25/2017 - 00:00
Hypospadias is a common congenital malformation of the male genital tract. The most frequent complication after hypospadias repair is urethrocutaneous fistula (1). Its incidence has been reported up to 35% worldwide (2). The diagnosis of these fistulas is sometime challenging particularly with tiny and multiple fistulas. Usually parents complain of urinary spraying, sprinkling or passing a single stream of urine from the undersurface of the penis after the surgery. Urethrocutaneous fistulas are not always visible on physical examination.
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How to treat an overactive bladder with natural remedies

MedicalNewsToday - Mon, 04/24/2017 - 10:00
In this article, learn about the symptoms of an overactive bladder, when a doctor should be consulted, and natural remedies to treat an overactive bladder.
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Letter to the Editor

Urology (Gold Journal) In Press - Mon, 04/24/2017 - 00:00
We read with great interest the recent manuscripts by Pak et al.1 and Borza et al.2, each who investigated open vs robotic cystectomy regarding outcomes and 30-day readmissions, respectively. We applaud the authors for their analyses comparing these two techniques of radical cystectomy. We believe that they are an important contribution, as the benefit of incorporating robotic surgery for radical cystectomy remains unclear. To date, there are no published large, multi-center randomized controlled comparative studies trials on this topic.
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Minimally Invasive Inguinal Lymphadenectomy in the Management of Penile Carcinoma

Urology (Gold Journal) In Press - Mon, 04/24/2017 - 00:00
To report and analyze the outcomes of endoscopic inguinal lymph node dissection (E-ILND), inclusive of video endoscopic ILND (VEIL) and robotic-assisted ILND (RAIL) approaches, in the largest reported series to date.
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Prediction of pediatric PCNL outcomes using contemporary scoring systems

To evaluate the applicability of contemporary percutaneous nephrolithotomy (PCNL) scoring systems in pediatric patients and to compare their predictive power for postoperative outcomes.
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Reply

Urology (Gold Journal) In Press - Mon, 04/24/2017 - 00:00
We appreciate the editorial comments. There has been substantial heterogeneity among published studies that explore the capabilities of detecting prostate cancer with multiparametric magnetic resonance imaging (mpMRI).1-3 Not surprisingly, differences in patient population, magnetic field strength, techniques, reference standard, methodology, reader experience, and interpretation criteria have resulted in a broad range of negative predictive values from 63% to 98%.1,2
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Editorial Comment

Urology (Gold Journal) In Press - Mon, 04/24/2017 - 00:00
Multiple studies have demonstrated that multiparametric magnetic resonance imaging (mpMRI) can significantly improve the detection of prostate cancers belonging to Grade Groups ≥2 when compared with systematic transrectal ultrasound-guided biopsies.1 The ability of mpMRI to predict a negative systematic biopsy result has also been demonstrated, although to a lesser extent; this is considered one of the main potential benefits of mpMRI, as it could help reduce the number of unnecessary biopsies, cases of overtreatment, and any associated side effects.
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Among Active Surveillance Candidates Does Obesity Influence Tumor Aggressiveness and/or Location?

The CDC (Centers for Disease Control and Prevention) estimates that more than a third of Americans are obese. In regard to prostate cancer (PC), obesity is linked to more aggressive cancers and increased PC mortality but a decreased risk of low grade PC.1 Indeed, at nearly every stage of disease obesity makes a more aggressive cancer. Obesity increases the risk of recurrence after surgery and radiation, and even increases the risk of castrate resistant PC after androgen deprivation therapy.1 The lone exception appears to be among men with metastatic castrate resistant PC.
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